Butler's Pharmacy has been around since 1919. The store features a navy blue Rexall sign. I believe these signs are older than the more common orange and blue neon signs like the one at the Stantonsburg Drug Co. If these blue oval signs are not older, they are at least rarer. [map]

The Stantonsburg Drug Co. was established in 1912. The store moved here in 1967 and must have brought this neon sign with them. The plastic sign looked like it might date from 1967. By 2021, these signs were gone.

Parson's Drugs was established in 1875. The store features both porcelain enamel and backlit plastic signs. [map]

The Chase Pharmacy sign never had neon, as evidenced by the dual lights installed on both sides of the sign. The store must have gone by another name originally since it has tacked on panels above and below. The bottom of the sign surely reads "Drugs." Those panels have been there since at least 2007. There were still Rexall panels on the front of the building in 2016. [map]